PrimerConverter

There's a blog article on how you can use this utility to create a."Primer Database" from an Excel spreadsheet of primers. You can then use that database to quickly scan any sequence for primer binding sites using the Nucleic Acid Subsequence analysis function.

PrimerConverter 2.0

MacVector 12.6 Updater

If you had a valid maintenance contract with MacVector, Inc on May 1st 2012, you are eligible to receive the MacVector 12.6 release. You can download the latest updater from this link. To determine if your license will be valid, choose the MacVector->About MacVector menu item - the resulting dialog will display your license details, including the date your maintenance agreement will expire. Click here for more details of the changes and new features in MacVector 12.6.

MacVector 12.6 User Guide

Here's the latest electronic version of the User Guide, updated to include the functionality added to MacVector 12.5 and 12.6.

MacVector 12.6 User Guide

MacVector 12.5.1 Updater

If you had a valid maintenance contract with MacVector, Inc on October 1st 2011, you are eligible to receive the MacVector 12.5 release. You can download the latest updater from this link. To determine if your license will be valid, choose the MacVector->About MacVector menu item - the resulting dialog will display your license details, including the date your maintenance agreement will expire. Click here for more details of the changes and new features in MacVector 12.5.

MacVector 12 User Guide

This version of the User Guide includes all of the functionality present in MacVector 12.0. You can grab a PDF copy of the manual from this link.

Download MacVector 12 User Guide

MacVector 12.0.6 Updater

If you had a valid maintenance contract with MacVector, Inc on December 1st 2010, you are eligible to receive the MacVector 12 release. You can download the latest updater from this link. To determine if your license will be valid, choose the MacVector->About MacVector menu item - the resulting dialog will display your license details, including the date your maintenance agreement will expire. Click here for more details of the changes and new features in MacVector 12. There's also a blog article on the new release.

MacVector 11.1.2 Updater

If you had a valid maintenance contract with MacVector, Inc on December 1st 2009, you are eligible to receive the MacVector 11.1.2 release. You can download the updater from this link. To determine if your license will be valid, choose the MacVector->About MacVector menu item - the resulting dialog will display your license details, including the date your maintenance agreement will expire. Click here for more details of the changes and new features in MacVector 11.1 and here for the bug fixes in MacVector 11.1.2. There's also a blog article on the new release.

Getting Started Guide

Need help just getting going with MacVector, importing sequences and running your first analysis? Want to create new cloning vectors and don't know how to start? Download our new Getting Started Guide

MacVector Workshop Manual (version 12.5)

This document introduces you to many of the new functions and features added in MacVector 10.0 through 12.5 using a hands-on tutorial approach.

MacVector 12.5 Workshop

MacVector 11.0 User Guide

This is the revision of the MacVector User Guide to match the release of MacVector 11.0 and was published in Dec 2009. We update the User Guide approximately once per 18 months.

MacVector 11 User Guide

MacVector 11 Updater

If you had a valid maintenance contract with MacVector, Inc on July 1st 2009, you are eligible to receive the MacVector 11.0 release. You can download the updater from this link. To determine if your license will be valid, choose the MacVector->About MacVector menu item - the resulting dialog will display your license details, including the date your maintenance agreement will expire. Click here for more details of the changes and new features in MacVector 11.

MacVector 10.6 Updater

All MacVector 10.5 users (including MacVector 10.5.1, 10.5.2 and 10.5.3) should immediately upgrade to version 10.6 using this installer. The new version combines all of the bug fixes and also adds support for reading Vector NTI database files.

MacVector 10.6 User Guide

This is the latest revision of the MacVector User Guide (March 2009). We update the User Guide approximately once per year.

MacVector 10.6 User Guide

Screencasts

Check out these videos of common workflows in MacVector.

Older Updaters

MacVector 9.5.2

This updater will upgrade MacVector 9.5, MacVector 9.5.1, MacVector+Assembler 9.5 or MacVector+Assembler 9.5.1 to version 9.5.2. The updater will NOT work on any previous versions of MacVector. Please contact sales@macvector.com if you wish to upgrade an earlier version. The download is a disk image file and should extract and mount automatically. Double-click on the MacVector 9.5.2 Updater application and follow the on-screen instructions. See the MacVector 9.5.2 Release Notes

MacVector 9.5.2 Updater

MacVector 9.0.2

This updater will upgrade MacVector 9.0 or MacVector 9.0.1 to the latest release, MacVector 9.0.2. The updater will NOT work on any previous versions of MacVector. Please contact sales@macvector.com if you wish to upgrade an earlier version. The download is a disk image file - double-click on it to mount the MacVector 9.0.1 updater disk if it does not mount automatically, then double-click on the MacVector 9.0.2 Updater application and follow the on-screen instructions to upgrade your copy.

MacVector 9.0.2 Updater

MacVector 8.1.2

This updater will upgrade any release of MacVector 8.x to 8.1.2, the last release in the MacVector 8.x series. MacVector 8.1.2 is the last version of MacVector capable of running under Mac OS 9. This updater will not work on versions of MacVector prior to version 8.0. It is supplied as a stuffit archive, meaning that you must have the free Stuffit Expander application installed on your computer to be able to extract the files. Once the files have been extracted, double-click on the MacVector 8.1.2 Updater application and follow the on-screen instructions to upgrade your copy.

MacVector 8.1.2 Updater

MacVector 7.2.3

This updater will upgrade any release of MacVector 7.1.x or 7.2.x to version 7.2.3. This updater will not work on versions of MacVector prior to version 7.1. It is supplied as a stuffit archive, meaning that you must have the free Stuffit Expander application installed on your computer to be able to extract the files. Once the files have been extracted, double-click on the MacVector 7.2.3 Updater application and follow the on-screen instructions to upgrade your copy.

MacVector 7.2.3 Updater

Data Sheets

These are the data sheets for MacVector and MacVector Assembler. They are in PDF format and can be read using the Mac OS X Preview application or Adobe Acrobat Reader.

MacVector Data Sheet

Assembler Data Sheet

Tutorials

Use these tutorials to learn more about MacVector and Assembler. They are in PDF format and can be read using the Mac OS X Preview application or Adobe Acrobat Reader. Further tutorials are available here.

Cloning Clipboard Tutorial

Autoannotation Tutorial

Sequence Confirmation Tutorial

Contig Assembler Tutorial

Click Cloning Tutorial

Gateway and TOPO Cloning Tutorial

Primer Design Tutorial

Next Generation Sequencing Reference Assembly Tutorial

Utility Applications

These utilities are provided "AS IS". If you do find bugs, please let us know and we will fix them when we get chance. However, please do not rely on them for critical applications. Unless otherwise specified, these are universal binaries that require a minimum of OS X 10.4.

REBaseConverter

You can use this utility to generate Restriction Enzyme files in MacVector formatfrom REBase data files. You can download the raw data files in a suitable format for the utility from this REBASE link maintained by New England Biolabs.

Download REBASEConverter

Support Files

Restriction Enzymes

This zipped folder contains the latest release of the REBASE Restriction Enzyme Database (release 111 from November 2011), formatted for use with MacVector. After you download the file, it should appear as a folder in your downloads folder. Copy the Restriction Enzyme files from within the downloaded folder into your MacVector Restriction Enzymes folder.

REBASE release 111 for MacVector

Methylated Restriction Enzyme Sites

This restriction enzyme file contains a list of recognition sites of enzymes that are blocked by either the E. coli Dam or Dcm methylase activities. The name of each recognition site is preceded by either "DAM-" or "DCM-" indicating the methylase that will block activity. For more information on how to use this file to identify cleavage sites that will be blocked by the methylase activity, please check out this blog post.

Methylation-Sensitive Restriction Enzymes.renz.