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MacVector, Inc. develops powerful but easy to use Macintosh applications for Molecular Biologists to simplify and speed up the analysis, manipulation, assembly and documentation of DNA and protein sequences.
MacVector is a comprehensive Macintosh application that provides sequence editing, primer design, internet database searching, protein analysis, sequence confirmation, multiple sequence alignment, phylogenetic reconstruction, coding region analysis, and a variety of other functions. MacVector is widely regarded as the most intuitive, easy to use program available for sequence analysis. More information on MacVector.
Assembler is an add-on module for MacVector that provides a simple graphical interface to the phred, phrap and cross_match contig assembly algorithms from the University of Washington, the popular Bowtie fast reference alignment program for Next Generation Sequencing projects and the Velvet de novo assembler for NGS data. Assembler must be purchased separately from MacVector. More details.
If you have relatively minimal sequence editing and analysis needs, or you just want to view, print and/or convert sequence files sent to you by a colleague, to check out our new MacVector Free product. It doesn't have all the advanced bells and whistles of the full release, but it might be just what you are looking for. Note that MacVector Free does require a Macintosh computer running OS X 10.5 or later.
The Quicktest Primer interface displays one-out restriction sites and lets you interact with them to instantly see the effect of changing the site on overlapping open reading frames. A double-click introduces the required mutation.
Assembler provides an intuitive interface that lets you directly view, analyze and edit both phrap and velvet NGS and ABO assemblies. (Click image to enlarge.)
Watch video tutorials on MacVector techniques
MacVector Cloning Edition
There is a new cost-effective version of MacVector available, targeted at users who want the power of MacVector's graphical annotation, clone construction and primer design tools, but without all of the bells and whistles of the full version. Click here for details of the new Cloning Edition. Which edition is right for you? Here's a handy functional comparison chart.
MacVector 14 Released!
We are pleased to announce the first fully 64-bit version of MacVector. Along with the performance boost when working with large sequences and alignments, there are significant enhancements to primer handling (including support for primer databases) and NGS data. You can read about the new functionality here and determine your eligibility for a free update here. The full installer is available to download on this page.
MacVector 13.5.5 Updater
There is a bug-fix release of MacVector 13.5.x available for download here.
MacVector 13.5 Avaliable!
There's a brand new release of MacVector available with enhancements to better support NGS data, aligning to circular sequences, speedy dot-plots and much, much more. You can read about the new functionality here and determine your eligibility for a free update here. The full installer is available to download on this page.
MacVector 13.0.7 Released!
Sorry about the quick update, but we finally tracked down the source of a critical issue for our European customers. We added a few US fixes too! This is a bug-fix update that should be installed by all users of MacVector 13. The bugs fixed are listed in the Release Notes and download the installer here.You can read about the new features in MacVector 13. To see if you are eligible to run MacVector 13, please view this page.
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Check out our Getting Started Guide
There's a useful Getting Started Guide to help new users get going with MacVector.
We have a blog with contributions from a selection of MacVector, Inc staff discussing a variety of subjects from OS X through bioinformatics, to the challenges of running a small multi-national company.